The study show the predominating emm sequence type of GAS in some regions of China is emm1, emm18, emm12, emm69 and emm110, this result provides an useful guideline to develop the M-type specific vaccine for RF in a specific area of endemicity.

• 我国部分地区A群链球菌emm基因分型主导型为emm1、18、12、6 9、110等菌型。