The side product was reused via rearrangement of methyl 3-bromolevulinate to methyl 5-bromolevulinate (5-MBL) and the yield of 5-MBL was thus improved to 45% from an earlier reported value of 30%.

• 同时利用3-溴乙酰丙酸甲酯等溴化物的分子内重排和歧化反应，对溴化反应生成的副产物回收再利用，将中间产物5-溴乙酰丙酸甲酯的产率从文献值30%25提高到45%25。