The rule of double effect is widely uesd in end-of-life care,administration of medication to relieve pain but it may lead to severe side effect,even death,it is acceptable ethically.

• 双重效应原则常用于临终患者的治疗中,应用药物为患者解除痛苦,但可能导致患者严重不良反应甚至死亡,这在伦理上是可以接受的。