The ribozyme gene which specifically cleaved 12-lipoxygenase mRNA was designed, synthesized and cloned ac cording to hammer-head ribozyme model.

• 根据锤头状核酶(Ribozyme)的作用模式，设计、合成并克隆了特异性切割12-脂加氧酶(12-LO)mRNA的核酶基因。