The results showed that cetirizine significantly inhibited PCA in rats, and effectively reduced the contraction of the uterus in Schultz-Dale reaction.

• 结果表明：西替利嗪对大鼠同种被动皮肤过敏反应有显著的抑制作用，大中小三组间有明显的量效关系，大中剂量组的作用优于扑尔敏，小剂量组与扑尔敏作用相当。