The results showed that a mutant L 3 195 with inheritable qualities whose 4AD transformation productivity was 116% higher than that of its parent strain and produced no androst 1,4 diene 3,17 dione was obtained via the third method.

• 结果表明 ,被照菌株产 1能力有不同程度的提高。 当菌株经紫外光照射后再以不同剂量 YAG倍频激光照射 ,获得一株高产优质突变株 L- 3- 195 ,产 1能力提高了116%25 ,且不再产生结构类似副产物雄甾二烯二酮 ,经 4次传代 ,突变株遗传性状稳定。