The results show ed that the pyramidal cells in the hippocampal CA3 area were also related to the onset of EAE, and WD could reduce the pathological lesions in the guinea pigs w ith EAE.

• 结果发现应用温阳补肾方可减轻EAE豚鼠的病理损害；海马CA-3区的锥体细胞也参与了EAE的发病过程。