The results sbowed that the gene mutation rate of PZA, SM, RFP,INH and EMB resistance in those clinically isolated strains was 42 7%,71 7%,78 9%,68 6% and 43 9%, respectively.

• 结果表明 ,耐吡嗪酰胺 (PZA)pncA基因 ,耐链霉素 (SM)rpsL基因 ,耐利福平 (REP)rpoB基因 ,耐异烟肼 (INH)katG基因 ,耐乙胺丁醇 (EMB)embB基因的突变率分别为 4 2 7%25 ,71 7%25 ,78 9%25 ,6 8 6%25 ,4 3 9%25。