The results indicated that silica caused mainly time and dose-dependent inhibitory effect on active oxygen species release of macrophages, and the inhibitory effect was closely related to silica-induced membrane injury.

• 结果表明,SiO_2对肺泡巨噬细胞活性氧的释放主要呈剂量与时间依赖性的抑制效应,这一抑制效应与SiO_2对细胞质膜的损伤作用密切相关。