The recombinant plasmid pBudCE4.1-S9K/mIL-12 was successfully constructed and expressed in vitro,which laid a foundation of gene therapy of tumors with granulysin and mIL-12.

• 已成功构建真核表达质粒pBudCE4.；1-S9K/mIL-12；并能体外表达；为下一步利用颗粒溶素与mIL-12基因治疗肿瘤奠定了基础。