The proband was a 9-year-old boy, with reticular pigmentation of the skin, leukoplakia in the oral mucosa, dystrophy of all nails and disproportionate dentition.

• 先证者男,9岁。全身呈网状棕黑色色素沉着,口腔黏膜白斑,牙齿排列不整齐,20甲营养不良。