The objective of this article was to review progress in the clinical studies and therapies on the disease, especially NSAID therapy and total knee replacement.

• 本文就近年来国内外对本病的临床研究及治疗，特别是药物非甾体抗炎药(NSAID)的治疗作用和全膝关节置换术等热点问题进行了综述。