The nineteen years old Catholic college girl Emily Rose (Jennifer Carpenter) dies a couple of days after being submitted to an exorcism carried out by her parish priest, Father Moore (Tom Wilkinson).

• 神父(汤韦坚逊饰演)为受尽邪魔愚弄的大学生艾美莉(珍妮花加芬达饰演)进行驱魔仪式后，艾美莉的生命竟然结束。