The model of heroin-addicted rat is firmly established by the subcutaneous injection of gradually-increased dosages of heroin . This method can made the rats become addicted to heroin in 28 days.

• 用递增法皮下注射海洛因建立的海洛因成瘾大鼠模型,可在28天内形成海洛因依赖模型,该模型稳定可靠。