The liver is the majority of medicines transformation metabolism place, when liver metabolism, some medicines itself and its metabolite may have direct or the indirect toxic damage to the liver cell.

• 肝脏是大部分药物转化代谢的场所,一些药物在肝脏代谢时,其本身或其代谢产物可对肝细胞产生直接或间接的毒性损伤。