The inhabiting effect was dose dependent.[Conclusion]Alendronate has the inhabiting effects of oil bone resorption and the differentiation of bone marrow cells into osteoclast-like cells in vitro.

• [结论]阿伦膦酸钠可抑制骨髓细胞体外培养中破骨样细胞的形成，体外可抑制破骨细胞骨吸收作用。