The inactivation occurred before noticeable conformational change during CK oxidization, which proved that the active sites of the enzyme display more conformational flexibility.

• 肌酸激酶起初微小的结构变化就会导致酶活性的迅速丧失，而且其的失活先于明显可测的整体构象变化，酶分子的活性部位处于柔性区域内。