The genetic disorder ataxia telangiectasia (AT) is characterized by immunodeficiency,progressive cerebellar ataxia, gonadal abnormalities, radiosensitivity, and cancer predisposition.

• 基因缺陷所致共济失调-毛细血管扩张症(AT)表现为免疫缺陷、进行性共济失调、性腺发育异常、辐射敏感和易患癌症等。