The formation rate of metabolites for S (-) OFLX was faster than that for R (+) OFLX. There were significant differences between two enantiomers for their Vmax,Km and Clint.

• S－（－ ）－OFLX代谢物的生成量和生成速度均大于R－（＋ ）－OFLX，两对映体的酶动力学参数也有显著差异。