The factors that induce endothelial cell injury are endotoxin,bilirubin,bile acid,hyperlipemia,operation and tumor in obstructive jaundice. Meanwhile,both the coagulation and anticoagulation are changing.

• 梗阻性黄疸时损伤内皮细胞的因素有内毒素、胆红素、胆汁酸盐、高血脂、手术创伤和肿瘤等,梗阻性黄疸时血管内皮细胞促凝功能与抗凝功能均发生改变。