The expression of p16 and PCNA in 22 cases of thyroid carcinoma and 20 cases of thyroid adenoma was studied by immunohischemistry.

• 应用免疫组化LSAB法对22例甲状腺癌及20例甲状腺腺瘤的突变型P~(16)蛋白表达研究；结果发现:P~(16)甲状腺癌和甲状腺腺瘤表达率分别为45%25及10%25；两者表达率有显著性差异(P