The expression of TLR2 mRNA in kidney tissues was markedly upregulated at 6h after CLP,peaked at 12h and kept in high level up to 24h,and the expression change of TLR2 protein was identical with the TLR2 mRNA expression.

• CLP术后8、12、24hTLR2mRNA表达均明显高于假手术组,TLR2蛋白表达与TLR2mRNA表达的变化规律相一致,均是12h达峰值,持续至伤后24h;