The expression of NOS, especially NOS3, has close relationship with the differentiation, TNM stage, lymphoid metastasis and prognosis of ESC.

• ESC组织的分化程度、TNM分期、淋巴结转移情况和预后与NOS尤其是NOS3有密切关系。 NOS的检测可作为ESC生物学行为和预后评价的参考指标。