The ex act mechanism was unknown,it related to the clonal deletion,clonal anergy,clo nal ignorance,immune deviation,clonal abortion,receptor editing,anti-idioty pe antibody and suppressor cells.

• 口服耐受的机制尚未完全明了,可能与克隆清除、克隆无能、克隆忽视、抗独特型抗体或抑制细胞有关。