The effect of bone substance loss and change of the bone microstructure on the mechanical properties of cance llous bone is discussed based on the homogenization theory.

• 利用均匀化理论研究了骨量丢失和微结构改变对松质骨力学性质的影响,得到结论:(1)骨量丢失初期弹性模量下降的速度较快,大约是骨量丢失速度的2倍。