The decrease of big artery dilatation, the increase of SBP and the increase of pulse pressure were the main reasons of increase of left ventricle burthen and left ventricular hypertrophy.

• 血压升高使大动脉扩张性降低，导致收缩压进一步升高，脉压增大，而脉压增大反过来又增加了动脉壁搏动负荷，导致大动脉损害加重, 大动脉扩张性进一步降低，这样就形成了一个恶性循环，最终造成左心室负荷增加和左心室肥厚。