The contractile response of SO to KCl increases while the activities of BKCa and KV in SO cells decrease in HC rabbits, which might be one of the reasons why SO dysfunction is caused in the condition of HC.

• HC兔SO肌环的收缩反应增强；SO细胞BKCa及KV通道活性降低；BKCa通道蛋白表达量降低；这可能是导致HC兔发生SO功能紊乱的原因之一.