The content of psoralen and isopsoralen are 0. 89 mg/g and 1.03mg/g respectly in Shishenwan. SFE CGC method can be used in the quality control of Chinese patent medicinals.

• 结果四神丸中的补骨脂素和异补骨脂素的含量分别为：补骨脂素0.；89mg/g，异补骨脂素1