The content of expression of occludin was the most in group 2, less in group 1, and the least in group 3. Conclusion AGEs may promote the abnormal proliferation of Miller cells and inhibit the expression of occludin in BREC.

• 添加正常Miller细胞上清液组紧密连接蛋白表达量最多,未添加任何细胞上清液组次之,添加AGEs作用后的Miller细胞上清液组更少。 结论AGEs能促进Miller细胞异常增殖、抑制BREC表达紧密连接蛋白。