The clinical therapeutic effectiveness was assessed with the Hamilton Depressive Scale (HAMD) and Clinical Global Impression (CGI) ,while adverse reactions were appraised with the Treatment Emergent Symptom Scale(TESS).

• 采用汉密尔顿抑郁量表(HAMD)、临床总体评定量表(CG I)评定临床疗效,不良反应量表(TESS)评定不良反应。