The authors call for additional research on the immune response to vaccinia to clarify why atopic dermatitis predisposes to eczema vaccinatum and to develop preventive strategies.

• 作者呼吁对牛痘引起的免疫反应进行进一步的研究，以确认为何遗传过敏性皮肤炎患者易发生牛痘性湿疹，并发展预防策略。