The SAP mouse model induced by caerulein plus LPS has the same pathological characteristics of human SAP, which can be used in human SAP research.

• 由本实验结果显示，雨蛙素联合脂多糖致小鼠重症急性胰腺炎模型具有人类重症急性胰腺炎的病理特徵，为非创伤性，成模快速稳定，重复性好；