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The Gemini cationic surfactant 1?3-dis(n-octadecyldimethylammonium chloride)-isopropanol was prepared using n-octadecyldimethylamine (OTA) and epichlorohydrin (EPIC) through the middle product n-octadecylglycidyldimethylammonium chloride (OGDMAC).

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