The E1A gene can effectively inhibit cervical carcinoma tumor growth in nude mice and the mechanism may relate to the E1A-induced increased expression of the caspase-3 gene and the decreased expression of the survivin gene.

• E1A基因能够明显抑制人宫颈癌细胞裸鼠移植瘤的生长,该作用可能与E1A基因激活Caspase-3基因和降低Survivin基因的表达有关。