Testosterone (T) and its metabolite dihydrotestosterone (DHT) are well-known androgens exert their effects through binding to the androgen receptor (AR), which is a transcription factor.

• 雄性素与其受体(AR)结合后构型改变，AR与原先相结合的蛋白质脱离，改而结合另一群蛋白质形成新的蛋白质复合体。