Telithromycin is an important representative of ketolides with excellent antibacterial properties and not easy to induce antibiotic resistance.The synthesis development is summarized.

• 特利霉素是酮内酯抗生素的重要代表；它对很多耐药菌有活性且不易引起耐药性.；作者对特利霉素的合成做了综述