TPA (12-0-tetradecanoylphorbol 13-acetate), a PKC activator, inhibited the expression of PAX-8 gene stimulated by TSAb, which was reversed by the PKC inhibitior (Calphostin C) .

• 蛋白激酶C(PKC)激活剂佛波酯(TPA)和抑制剂则无上述效应,TPA抑制TSAb刺激的PAX-8基因的表达,此作用可被PKC抑制剂(Calphostin C)逆转。