TH, AADC and GCH were effectively coexpressed in transduced cells with three separate AAV vectors, AAV-TH, AAV-AADC and AAV-GCH. Furthermore, the coexpression resulted in an effectively spontaneous dopamine production in cotransduced cells.

• TH、AADC、GCH的可在使用三种AAV载体 (AAV TH、AAV AADC、AAV GCH)转导的细胞中有效共表达 ,进一步分析发现 ,这种共表达可使该细胞有效地自发生成多巴胺。