Suppression of target of rapamycin, a downstream effector of phosphoinositide 3-kinase, also prevented lipofuscin accumulation in the heart.

• 雷帕霉素作用点（即为磷酸肌醇-3激酶基因下游的受动器）的抑制也同样能够阻止脂褐质在心肌的积聚。