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Successful research of GCLE [(6R-trans)-5-Thia-l-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-chloromethyl-8-oxo-7-[(phenylacetyl)amino]-diphenylmethyl ester] provides new synthetic route for researching and developing new cephalosporin antibiotics.

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