Studies indicate that peripheric injection of CRF inhibits gastric and ileum motility, stimulate duodenal and colonic motor function through its direct effect with CRF receptors.

• 研究表明，外周注射CRF可直接作用于胃肠道相应受体，引起胃排空延缓，十二指肠局部收缩性增加，回肠活性减弱，结肠运动增强。