Starting with the readily available isatin, two designated key cyclization precurors 25 and 26 were synthesized respectively by 5 steps and 6 steps reactions ,with Wittig reaction and Corey-Chaykorsky reaction as key steps.

• 以商品可得的吲哚醌为起始原料,分别经过5步和6步以Wittig烯烃化,Corey-Chaykorsky反应为关键步骤的合成路线,得到2个用于的环合反应的前体亚胺25和26。