So the effects of LCN on tachycardia-induced acute atrial electrical remodeling and electrophysiological change induced by atrial ischemia were studied.

• 据此,我们提出假说:外源性LCN可改善AF时缺血心肌的能量代谢,减轻AF时的心房电重构,并在AF诱发的犬心房电重构模型和单纯结扎犬右冠状动脉心房分支造成的心房局部缺血模型上加以证实。