Significant downregulate of GR mRNA and upregulate of IL-6 mRNA was found in kindled rats, which can be abated or reversed by some AEDs companied with improving of seizure and EEG No expression of IL-2 mRNA was detected in all groups.

• 电点燃大鼠机体内 GR mRNA表达明显下调，IL-6 mRNA表达升高，有些抗癫痫药物能缓解或逆转这些改变，抽搐发作和脑电图也有改善。 各组海马均没有IL-2表达。