Severe burn could induce the expression of PMN CD11b/CD18 which may be the main adhesion molecule participating in the increasing PMN adhesion to EC due to severe burns.

• 严重烧伤能使外周血PMNCD11b/CD18表达明显增高，CD11b/CD18不但介导基础状态下的PMN粘附，更是介导烧伤后引起的大量PMN与PMEC粘附的主要分子。