Several classes of small molecules have been described to induce the G-rich single-stranded overhang of telomeric DNA to fold into 4-stranded Gvquadruplex struc...

• 这些小分子化合物有强大的端粒酶活性抑制和诱导肿瘤细胞快速衰老的作用,靶向G-四螺旋提供了新颖的广谱的抗肿瘤治疗策略。