RECK gene, a new MMP inhibitor, is able to inhibit MMPs to inhibit the invasiveness and metastasis of the malignancies. Update on the research of the RECK gene was summarized.

• RECK基因是近年发现的新型基质金属蛋白酶(MMP)抑制剂,研究表明,其可在转录后水平抑制多种MMP的表达,抑制肿瘤血管形成,从而抑制肿瘤的侵袭及转移。作者就RECK基因的研究进展作一综述。