RAS inhibition can reduce cell apoptosis of alveolar epithelial cells and endothelial cells, interfere with the inflammation cascade, and decrease fibroblast activity during tissue repair process.

• RAS抑制可以通过多种分子机制抑制肺泡上皮细胞和血管内皮细胞的凋亡,抑制炎症级联反应和细胞外基质沉积,而使肺纤维化病变减轻。