Prognosis of chronic hepatitis B has been improved significantly because of the clinical application of nucleoside/nucleotide analogues, such as lamivudine, adefovir dipivoxil, entecavir.

• 拉米夫定、阿德福韦酯和恩替卡韦等核苷/核苷酸类似物的临床应用，大大改善了慢性乙型肝炎的预后。