Previous studies have shown the association between colorectal carcinogenesis and the mutation of K-ras and c-myc oncogenes, inactivation of tumor suppressor genes such as P53, APC, DCC, MCC, P53 etc.

• 研究表明大肠癌的发生与K-ras癌基因突变和P53、APC和DCC等抑癌基因失活有关。